(19)

(11)

EP 0 873 142 A1

(12)

(43) Date of publication: 28.10.1998 Bulletin 1998/44 (21) Application number: 96916950.0 (22) Date of filing: 03.06.1996

(51) International Patent Classification (IPC):  C12Q 1/ 42( . ) G01N 33/ 68( . ) C12Q 1/ 48( . ) (86) International application number: PCT/US1996/008332 (87) International publication number: WO 1996/040276 (19.12.1996 Gazette 1997/03)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 07.06.1995 US 19950488156 (71) Applicant: Sugen, Inc. Redwood City, CA 94063 (US)	(72) Inventors: ULLRICH, Axel D-82152 Martinsreid (DE) APP, Harald Hillsborough, CA 94010 (US) HIRTH, Klaus, P. San Francisco, CA 94114 (US) TSAI, Jianming San Francisco, CA 94118 (US) (74) Representative: Schüssler, Andrea, Dr.  Kanzlei Huber & Schüssler Truderinger Strasse 246 81825 München 81825 München (DE)