(19)
(11) EP 0 873 310 A1

(12)

(43) Date of publication:
28.10.1998 Bulletin 1998/44

(21) Application number: 96940966.0

(22) Date of filing: 11.12.1996
(51) International Patent Classification (IPC): 
C07D 213/ 30( . )
C07D 213/ 56( . )
C07D 213/ 53( . )
C07D 401/ 10( . )
(86) International application number:
PCT/CA1996/000838
(87) International publication number:
WO 1997/022585 (26.06.1997 Gazette 1997/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 15.12.1995 US 19950008766P
22.02.1996 GB 19960003723

(71) Applicant: MERCK FROSST CANADA INC.
Kirkland Quebec H9H 3L1 (CA)

(72) Inventors:
  • GUAY, Daniel
    Kirkland, Quebec H9H 3L1 (CA)
  • GIRARD, Yves
    Kirkland, Quebec H9H 3L1 (CA)
  • DUCHARME, Yves
    Kirkland, Quebec H9H 3L1 (CA)

(74) Representative: Horgan, James Michael Frederic 
Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) DIPHENYL PYRIDYL ETHANE DERIVATIVES AS PDE IV INHIBITORS