TRI-ARYL ETHANE DERIVATIVES AS PDE IV INHIBITORS - Patent 0873311

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EP 0 873 311 A1

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(43)	Date of publication:
	28.10.1998 Bulletin 1998/44

(21)	Application number: 96940967.0

(22)	Date of filing: 11.12.1996

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 4409^{( . )}
A61P 11/ 06^{( . )}
C07D 213/ 30^{( . )}
C07D 213/ 52^{( . )}
C07D 213/ 89^{( . )}

A61K 31/ 44^{( . )}
A61P 11/ 00^{( . )}
A61P 43/ 00^{( . )}
C07D 213/ 50^{( . )}
C07D 213/ 61^{( . )}

(86)	International application number:
	PCT/CA1996/000839

(87)	International publication number:
	WO 1997/022586 (26.06.1997 Gazette 1997/27)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

15.12.1995 US 19950008704P
26.03.1996 GB 19960006377

(71)	Applicant: MERCK FROSST CANADA INC.
	Kirkland Quebec H9H 3L1 (CA)

(72)	Inventors:
	GUAY, Daniel Kirkland, Quebec H9H 3L1 (CA) GIRARD, Yves Kirkland, Quebec H9H 3L1 (CA) DUCHARME, Yves Kirkland, Quebec H9H 3L1 (CA) BLOUIN, Marc Kirkland, Quebec H9H 3L1 (CA) HAMEL, Pierre Kirkland, Quebec H9H 3L1 (CA) GIRARD, Mario Kirkland, Quebec H9H 3L1 (CA)

(74)	Representative: Horgan, James Michael Frederic
	Merck & Co., Inc., Terlings Park, Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	TRI-ARYL ETHANE DERIVATIVES AS PDE IV INHIBITORS