(19)
(11) EP 0 874 639 A1

(12)

(43) Date of publication:
04.11.1998 Bulletin 1998/45

(21) Application number: 96937741.0

(22) Date of filing: 24.10.1996
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 3/ 00( . )
A61P 13/ 00( . )
A61P 29/ 00( . )
A61P 31/ 12( . )
A61P 35/ 02( . )
A61P 37/ 06( . )
C07K 7/ 08( . )
C07K 14/ 71( . )
 A61K 31/ 00( . )
A61P 3/ 10( . )
A61P 13/ 12( . )
A61P 31/ 00( . )
A61P 35/ 00( . )
A61P 37/ 00( . )
A61P 43/ 00( . )
C07K 14/ 47( . )
C07K 14/ 715( . )
(86) International application number:
PCT/US1996/017080
(87) International publication number:
WO 1997/015318 (01.05.1997 Gazette 1997/19)
(84) Designated Contracting States:
CH DE FR GB LI

(30) Priority: 27.10.1995 US 19950005944P
22.01.1996 US 19960010384P
20.02.1996 US 19960011799P

(71) Applicants:
  • MOUNT SINAI HOSPITAL CORPORATION
    Toronto, Ontario M5G 1X5 (CA)
  • ASAHI CHEMICAL INDUSTRY CO., LTD.
    Tokyo 100 (JP)

(72) Inventors:
  • VAN DER GEER, Peter
    Toronto, Ontario M4Y 2P8 (CA)
  • WILEY, Sandra
    Toronto, Ontario M4Y 2P8 (CA)
  • GISH, Gerald
    Don Mills, Ontario M3B 2J2 (CA)
  • PAWSON, Tony
    Toronto, Ontario M6P 3C6 (CA)
  • TOMA, Kazunori
    Sagamihara 229 (JP)

(74) Representative: Hale, Stephen Geoffrey, et al 
JY & GW Johnson, Kingsbourne House, 229-231 High Holborn
London WC1V 7DP
London WC1V 7DP (GB)

   


(54) PEPTIDE INHIBITORS OF A PHOSPHOTYROSINE-BINDING DOMAIN CONTAINING PROTEIN