(19)
(11) EP 0 874 833 A1

(12)

(43) Date of publication:
04.11.1998 Bulletin 1998/45

(21) Application number: 96944274.0

(22) Date of filing: 12.12.1996
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
A61K 31/ 423( . )
A61K 31/ 46( . )
A61P 1/ 00( . )
A61P 25/ 04( . )
A61P 25/ 22( . )
A61P 43/ 00( . )
C07D 413/ 04( . )
C07D 413/ 14( . )
C07D 453/ 02( . )
A61K 31/ 42( . )
A61K 31/ 4375( . )
A61K 31/ 496( . )
A61P 1/ 08( . )
A61P 25/ 18( . )
A61P 25/ 30( . )
C07D 261/ 20( . )
C07D 413/ 12( . )
C07D 451/ 06( . )
(86) International application number:
PCT/US1996/019569
(87) International publication number:
WO 1997/025317 (17.07.1997 Gazette 1997/31)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV RO SI

(30) Priority: 05.01.1996 US 19960583319

(71) Applicant: HOECHST MARION ROUSSEL, INC.
Cincinnati OH 45215-6300 (US)

(72) Inventor:
  • HRIB, Nicholas, J.
    Somerville, NJ 08876 (US)

(74) Representative: Macchetta, Francesco, et al 
GRUPPO LEPETIT S.p.A. Patent and Trademark Department Viale Gran Sasso, 18
20131 Milano
20131 Milano (IT)

   


(54) 4,5-DIHYDRONAPHTH 1,2-C]ISOXAZOLES AND DERIVATIVES THEREOF HAVING CNS ACTIVITY