(19)

(11)

EP 0 874 858 A1

(12)

(43) Date of publication: 04.11.1998 Bulletin 1998/45 (21) Application number: 96944469.0 (22) Date of filing: 13.12.1996

(51) International Patent Classification (IPC):  C07F 9/ 6571( . ) (86) International application number: PCT/US1996/020226 (87) International publication number: WO 1997/024361 (10.07.1997 Gazette 1997/30)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 29.12.1995 US 19950581147 29.12.1995 US 19950009375P 29.12.1995 US 19950009372P (71) Applicant: GILEAD SCIENCES, INC. Foster City, CA 94404 (US)	(72) Inventors: ARIMILLI, Murty, N. Fremont, CA 94555 (US) BISCHOFBERGER, Norbert, W. San Carlos, CA 94070 (US) JONES, Robert, J. Millbrae, CA 94030 (US) LEE, William, A. Los Altos, CA 94024 (US) PRISBE, Ernest, J. Los Altos, CA 94024 (US) (74) Representative: Ablewhite, Alan James, et al  MARKS & CLERK, 57/60 Lincoln's Inn Fields London WC2A 3LS London WC2A 3LS (GB)