(19)
(11) EP 0 876 355 A1

(12)

(43) Date of publication:
11.11.1998 Bulletin 1998/46

(21) Application number: 96942118.0

(22) Date of filing: 25.11.1996
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
A61K 31/ 4164( . )
A61K 31/ 4174( . )
A61P 9/ 00( . )
C07D 233/ 86( . )
A61K 31/ 415( . )
A61K 31/ 4166( . )
A61K 31/ 4439( . )
A61P 9/ 10( . )
(86) International application number:
PCT/US1996/019164
(87) International publication number:
WO 1997/019932 (05.06.1997 Gazette 1997/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV RO SI

(30) Priority: 28.11.1995 US 19950563325
28.11.1995 US 19950007654P
28.11.1995 US 19950007658P
28.11.1995 US 19950007661P
28.11.1995 US 19950007665P
28.11.1995 US 19950007666P

(71) Applicant: AMERICAN HOME PRODUCTS CORPORATION
Madison, New Jersey 07940-0874 (US)

(72) Inventors:
  • ELOKDAH, Hassan, Mahmoud
    Yardley, PA 19067 (US)
  • CHAI, Sie-Yearl
    Lawrenceville, NJ 08648 (US)
  • SULKOWSKI, Theodore, Sylvester
    Wayne, PA 19087 (US)
  • STRIKE, Donald, Peter
    St. Davids, PA 19087 (US)

(74) Representative: Mannion, Sally Kim, Dr., et al 
c/o Wyeth Laboratories, Huntercombe Lane South, Taplow
Maidenhead, Berkshire SL6 0PH
Maidenhead, Berkshire SL6 0PH (GB)

   


(54) 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION