(19)
(11) EP 0 880 584 A1

(12)

(43) Date of publication:
02.12.1998 Bulletin 1998/49

(21) Application number: 97903477.0

(22) Date of filing: 14.02.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 38/ 00( . )
C07K 14/ 52( . )
C12N 5/ 0735( . )
C12N 15/ 00( . )
C12R 1/ 91( . )
A61K 31/ 00( . )
A61P 43/ 00( . )
C12N 5/ 00( . )
C12N 5/ 10( . )
C12N 15/ 01( . )
(86) International application number:
PCT/GB1997/000426
(87) International publication number:
WO 1997/030151 (21.08.1997 Gazette 1997/36)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
LT LV SI

(30) Priority: 16.02.1996 GB 19960003244
31.05.1996 GB 19960011319

(71) Applicant: UNIVERSITY OF EDINBURGH
South Bridge, Edinburgh EH8 9YL (GB)

(72) Inventors:
  • DANI, Christian, Centre for Genome Research
    Edinburgh EH9 3JQ (GB)
  • CHAMBERS, Ian Paul, Centre for Genome Research
    Edinburgh EH9 3JQ (GB)
  • BEUHR, Mia Lydia, Centre for Genome Research
    Edinburgh EH9 3JQ (GB)
  • SMITH, Austin Gerard, Centre for Genome Research
    Edinburgh EH9 3JQ (GB)

(74) Representative: Ritter, Stephen David, et al 
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) CYTOKINE EXPRESSED BY DIA/LIF-DEFICIENT EMBRYONIC STEM CELLS FOR THE INHIBITION OF DIFFERENTIATION