(19)

(11)

EP 0 881 916 A2

(12)

(43) Date of publication: 09.12.1998 Bulletin 1998/50 (21) Application number: 97905227.0 (22) Date of filing: 20.02.1997

(51) International Patent Classification (IPC):  A61K 49/ 04( . ) A61K 49/ 22( . ) A61K 49/ 18( . ) (86) International application number: PCT/GB1997/000473 (87) International publication number: WO 1997/030736 (28.08.1997 Gazette 1997/37)

(84) Designated Contracting States: DE DK ES FR GB IE IT SE (30) Priority: 20.02.1996 GB 19960003547 (71) Applicant: NYCOMED IMAGING AS 0401 Oslo 4 (NO)	(72) Inventors: RAJAGOPALAN, Natarajan Wayne, PA 19807-6830 (US) OSTRANDER, Kevin Darryl Wayne, PA 19807-6830 (US) GUSTOW, Evan Wayne, PA 19807-6830 (US) DOTY, Brian Wayne, PA 19807-6830 (US) HARNISH, Phillip Wayne, PA 19087-6830 (US) (74) Representative: Cockbain, Julian, Dr.  Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)