(19)

(11)

EP 0 883 629 A1

(12)

(43) Date of publication: 16.12.1998 Bulletin 1998/51 (21) Application number: 97919879.0 (22) Date of filing: 28.02.1997

(51) International Patent Classification (IPC):  A61K 9/ 00( . ) A61K 47/ 18( . ) A61K 38/ 00( . ) A61K 38/ 17( . ) C07K 5/ 02( . ) (86) International application number: PCT/US1997/004051 (87) International publication number: WO 1997/031938 (04.09.1997 Gazette 1997/38)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE (30) Priority: 29.02.1996 US 19960012573P (71) Applicant: Emisphere Technologies, Inc. Hawthorne, NY 10532 (US)	(72) Inventor: MILSTEIN, Sam, J. Larchmont, NY 10538 (US) (74) Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät  Maximilianstrasse 58 80538 München 80538 München (DE)