(19)

(11)

EP 0 885 039 A1

(12)

(43) Date of publication: 23.12.1998 Bulletin 1998/52 (21) Application number: 97908045.0 (22) Date of filing: 05.03.1997

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) B01D 15/ 08( . ) C12M 1/ 00( . ) G01N 1/ 40( . ) B01D 15/ 00( . ) C07H 21/ 00( . ) C12N 15/ 10( . ) (86) International application number: PCT/US1997/003533 (87) International publication number: WO 1997/032645 (12.09.1997 Gazette 1997/39)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 06.03.1996 US 19960611926 (71) Applicant: AKZO NOBEL N.V. 6800 LS Arnhem (NL)	(72) Inventors: CHEMELLI, Benjamin, J. Durham, NC 27712 (US) ROBINSON, Donald Lakeland, FL 33809 (US) BORST, G., A., P. NL-5262 XC Vught (NL) JONES, Matthew, Arthur Raleigh, NC 27612 (US) GONZALES, Pamela, Jean Durham, NC 27712 (US) (74) Representative: Van Gent, Marieke, et al  N.V. Organon, Postbus 20 5340 BH Oss 5340 BH Oss (NL)