(19)
(11) EP 0 885 205 A1

(12)

(43) Date of publication:
23.12.1998 Bulletin 1998/52

(21) Application number: 97906712.0

(22) Date of filing: 24.02.1997
(51) International Patent Classification (IPC): 
C07D 295/ 12( . )
A61K 31/ 435( . )
A61K 31/ 437( . )
A61K 31/ 4402( . )
A61K 31/ 4409( . )
A61K 31/ 445( . )
A61K 31/ 4523( . )
A61K 31/ 47( . )
A61K 31/ 4725( . )
A61K 31/ 496( . )
A61P 7/ 02( . )
C07D 211/ 22( . )
C07D 213/ 81( . )
C07D 215/ 227( . )
C07D 295/ 14( . )
C07D 333/ 34( . )
C07D 333/ 40( . )
C07D 401/ 06( . )
C07D 215/ 22( . )
A61K 31/ 00( . )
A61K 31/ 4353( . )
A61K 31/ 44( . )
A61K 31/ 4406( . )
A61K 31/ 4427( . )
A61K 31/ 4465( . )
A61K 31/ 4545( . )
A61K 31/ 472( . )
A61K 31/ 495( . )
A61P 7/ 00( . )
C07D 209/ 08( . )
C07D 211/ 34( . )
C07D 213/ 82( . )
C07D 215/ 38( . )
C07D 295/ 155( . )
C07D 333/ 38( . )
C07D 401/ 04( . )
C07D 471/ 04( . )
(86) International application number:
PCT/US1997/002712
(87) International publication number:
WO 1997/031910 (04.09.1997 Gazette 1997/38)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 28.02.1996 US 19960012380P
27.03.1996 GB 19960006489

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • WAI, John
    Rahway, NJ 07065 (US)
  • DUGGAN, Mark, E.
    Rahway, NJ 07065 (US)
  • FISHER, Thorsten, E.
    Rahway, NJ 07065 (US)
  • HARTMAN, George, D.
    Rahway, NJ 07065 (US)
  • PERKINS, James, J.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James, et al 
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) FIBRINOGEN RECEPTOR ANTAGONISTS