SPIROCYCLE INTEGRIN INHIBITORS - Patent 0888344

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EP 0 888 344 A1

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(43)	Date of publication:
	07.01.1999 Bulletin 1999/01

(21)	Application number: 97919892.0

(22)	Date of filing: 17.03.1997

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International Patent Classification (IPC):

C07D 231/ 54^{( . )}
A61K 31/ 4178^{( . )}
A61K 31/ 423^{( . )}
A61K 31/ 4245^{( . )}
A61K 31/ 433^{( . )}
A61K 31/ 438^{( . )}
A61K 31/ 4709^{( . )}
A61K 31/ 55^{( . )}
A61P 7/ 02^{( . )}
A61P 9/ 10^{( . )}
A61P 27/ 02^{( . )}
A61P 35/ 04^{( . )}
C07D 261/ 20^{( . )}
C07D 401/ 12^{( . )}
C07D 403/ 14^{( . )}
C07D 413/ 14^{( . )}
C07D 471/ 04^{( . )}
C07D 519/ 00^{( . )}

A61K 31/ 416^{( . )}
A61K 31/ 4184^{( . )}
A61K 31/ 424^{( . )}
A61K 31/ 427^{( . )}
A61K 31/ 437^{( . )}
A61K 31/ 4439^{( . )}
A61K 31/ 506^{( . )}
A61P 3/ 14^{( . )}
A61P 9/ 00^{( . )}
A61P 19/ 10^{( . )}
A61P 29/ 00^{( . )}
A61P 43/ 00^{( . )}
C07D 271/ 12^{( . )}
C07D 403/ 12^{( . )}
C07D 413/ 12^{( . )}
C07D 417/ 14^{( . )}
C07D 498/ 10^{( . )}

(86)	International application number:
	PCT/US1997/004567

(87)	International publication number:
	WO 1997/033887 (18.09.1997 Gazette 1997/40)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

15.03.1996 US 19960013539P
08.05.1996 US 19960646896
14.03.1997 US 19970816580

(71)	Applicant: THE DU PONT MERCK PHARMACEUTICAL COMPANY
	Wilmington, Delaware 19898 (US)

(72)	Inventors:
	JADHAV, Prabhakar, Kondaji Wilmington, DE 19808 (US) SMALLHEER, Joanne, Marie Landenberg, PA 19350 (US)

(74)	Representative: Pett, Christopher Phineas, et al
	Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)

(54)	SPIROCYCLE INTEGRIN INHIBITORS