(19)
(11) EP 0 889 900 A1

(12)

(43) Date of publication:
13.01.1999 Bulletin 1999/02

(21) Application number: 97948160.0

(22) Date of filing: 05.11.1997
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 31/ 704( . )
A61K 38/ 00( . )
A61P 9/ 00( . )
C07H 15/ 252( . )
C07K 14/ 705( . )
C07K 16/ 28( . )
C12N 5/ 10( . )
C12P 21/ 08( . )
A61K 31/ 337( . )
A61K 33/ 24( . )
A61K 39/ 395( . )
A61P 35/ 00( . )
C07K 14/ 47( . )
C07K 16/ 18( . )
C07K 16/ 46( . )
C12N 15/ 09( . )
(86) International application number:
PCT/US1997/020006
(87) International publication number:
WO 1998/025946 (18.06.1998 Gazette 1998/24)
(84) Designated Contracting States:
AT CH DE ES FR GB IT LI NL SE

(30) Priority: 20.12.1996 SE 19960004731

(71) Applicant: IMCLONE SYSTEMS, INC.
New York, NY 10014 (US)

(72) Inventors:
  • DEJANA, Elisabetta
    I-20146 Milano (IT)
  • TELO, Paola
    I-25063 Gardone Val Trompia (IT)

(74) Representative: Grünecker, Kinkeldey, Stockmair & Schwanhäusser Anwaltssozietät 
Maximilianstrasse 58
80538 München
80538 München (DE)

   


(54) MONOCLONAL ANTIBODIES SPECIFIC TO ENDOTHELIAL CELL CADHERINS AND USES THEREOF