INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - Patent 0891333

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EP 0 891 333 A1

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(43)	Date of publication:
	20.01.1999 Bulletin 1999/03

(21)	Application number: 97920031.0

(22)	Date of filing: 01.04.1997

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International Patent Classification (IPC):

C07D 233/ 30^{( . )}
A61K 31/ 415^{( . )}
A61K 31/ 4166^{( . )}
C07D 213/ 57^{( . )}
C07D 233/ 54^{( . )}
C07D 233/ 66^{( . )}
C07D 401/ 14^{( . )}
C07D 403/ 14^{( . )}
C07D 409/ 14^{( . )}
C07D 417/ 06^{( . )}

A61K 31/ 00^{( . )}
A61K 31/ 4164^{( . )}
A61P 43/ 00^{( . )}
C07D 233/ 32^{( . )}
C07D 233/ 64^{( . )}
C07D 233/ 70^{( . )}
C07D 403/ 10^{( . )}
C07D 409/ 10^{( . )}
C07D 413/ 06^{( . )}
C07D 417/ 14^{( . )}

(86)	International application number:
	PCT/US1997/005383

(87)	International publication number:
	WO 1997/036875 (09.10.1997 Gazette 1997/43)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

03.04.1996 US 19960014592P
27.06.1996 GB 19960013462
24.07.1996 US 19960022582P
16.08.1996 GB 19960017257

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	ANTHONY, Neville, J. Rahway, NJ 07065 (US) STOKKER, Gerald, E. Rahway, NJ 07065 (US) GOMEZ, Robert, P. Rahway, NJ 07065 (US) SOLINSKY, Kelly, M. Rahway, NJ 07065 (US) WAI, John, S. Rahway, NJ 07065 (US) WILLIAMS, Theresa, M. Rahway, NJ 07065 (US) YOUNG, Steven, D. Rahway, NJ 07065 (US) HUTCHINSON, John, H. Rahway, NJ 07065 (US) HALCZENKO, Wasyl Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr., et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE