(19)
(11) EP 0 891 353 A1

(12)

(43) Date of publication:
20.01.1999 Bulletin 1999/03

(21) Application number: 97917669.0

(22) Date of filing: 27.03.1997
(51) International Patent Classification (IPC): 
C07D 233/ 64( . )
A61K 31/ 415( . )
A61K 31/ 4178( . )
A61P 1/ 16( . )
A61P 13/ 12( . )
A61P 27/ 02( . )
A61P 31/ 12( . )
C07D 233/ 54( . )
A61K 31/ 00( . )
A61K 31/ 4164( . )
A61P 1/ 00( . )
A61P 13/ 00( . )
A61P 27/ 00( . )
A61P 31/ 00( . )
A61P 35/ 00( . )
C07D 401/ 06( . )
(86) International application number:
PCT/US1997/005060
(87) International publication number:
WO 1997/036892 (09.10.1997 Gazette 1997/43)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 03.04.1996 US 19960014777P
09.08.1996 GB 19960016736

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventors:
  • DINSMORE, Christopher, J.
    Rahway, NJ 07065-0907 (US)
  • WILLIAMS, Theresa, M.
    Rahway, NJ 07065-0907 (US)

(74) Representative: Thompson, John Dr., et al 
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE