INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - Patent 0897303

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EP 0 897 303 A1

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(43)	Date of publication:
	24.02.1999 Bulletin 1999/08

(21)	Application number: 97916942.0

(22)	Date of filing: 27.03.1997

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 445^{( . )}
A61K 31/ 4523^{( . )}
A61P 1/ 00^{( . )}
A61P 9/ 00^{( . )}
A61P 13/ 12^{( . )}
A61P 27/ 02^{( . )}
A61P 31/ 10^{( . )}
A61P 43/ 00^{( . )}

A61K 31/ 4427^{( . )}
A61K 31/ 4465^{( . )}
A61K 31/ 454^{( . )}
A61P 1/ 16^{( . )}
A61P 13/ 00^{( . )}
A61P 27/ 00^{( . )}
A61P 31/ 00^{( . )}
A61P 35/ 00^{( . )}
C07D 401/ 06^{( . )}

(86)	International application number:
	PCT/US1997/004713

(87)	International publication number:
	WO 1997/036605 (09.10.1997 Gazette 1997/43)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

03.04.1996 US 19960014793P
09.05.1996 GB 19960009667

(71)	Applicant: MERCK & CO., INC.
	Rahway, New Jersey 07065 (US)

(72)	Inventors:
	GRAHAM, Samuel, L. Rahway, NJ 07065 (US) WILLIAMS, Theresa, M. Rahway, NJ 07065 (US) WAI, John, S. Rahway, NJ 07065 (US)

(74)	Representative: Thompson, John Dr., et al
	Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE