| (19) |
 |
|
(11) |
EP 0 899 268 A3 |
| (12) |
EUROPEAN PATENT APPLICATION |
| (88) |
Date of publication A3: |
|
07.07.1999 Bulletin 1999/27 |
| (43) |
Date of publication A2: |
|
03.03.1999 Bulletin 1999/09 |
| (22) |
Date of filing: 11.08.1998 |
|
|
| (84) |
Designated Contracting States: |
|
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE |
|
Designated Extension States: |
|
AL LT LV MK RO SI |
| (30) |
Priority: |
12.08.1997 GB 9717107
|
| (71) |
Applicants: |
|
- Baldwin, Jack Edward
Hinksey Hill,
Oxford OX1 5BH (GB)
- Adlington, Robert Michael
Oxford OX2 9HT (GB)
- Crouch, Nicholas Paul
Marden,
Nr. Tonbridge TN12 9SU (GB)
|
|
| (72) |
Inventors: |
|
- Baldwin, Jack Edward
Hinksey Hill,
Oxford OX1 5BH (GB)
- Adlington, Robert Michael
Oxford OX2 9HT (GB)
- Crouch, Nicholas Paul
Marden,
Nr. Tonbridge TN12 9SU (GB)
|
| (74) |
Representative: Pennant, Pyers et al |
|
Stevens, Hewlett & Perkins
1 Serjeants' Inn
Fleet Street
London EC4Y 1LL
London EC4Y 1LL (GB) |
|
| |
|
| (54) |
Process for the preparation of omeprazole and intermediate compounds |
(57) A strategy for synthesising omeprazole 10 starting from compound 1 as shown in the
diagram. Individual method steps 1→2, 2→3, 3→4, 4→5, 5→6, 6→7, and intermediate compounds
2, 3, 4, 5, 6 and 9 are also claimed as new.