PYRIDINYL-2-CYCLOPENTEN-1-ONES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS - Patent 0900201

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(11)

EP 0 900 201 A1

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(43)	Date of publication:
	10.03.1999 Bulletin 1999/10

(21)	Application number: 97917190.0

(22)	Date of filing: 22.04.1997

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61K 31/ 4402^{( . )}
A61K 31/ 4409^{( . )}
A61P 11/ 06^{( . )}
A61P 15/ 06^{( . )}
A61P 19/ 10^{( . )}
A61P 27/ 00^{( . )}
A61P 27/ 06^{( . )}
A61P 35/ 00^{( . )}
A61P 37/ 00^{( . )}
C07D 213/ 50^{( . )}
C07D 213/ 64^{( . )}

A61K 31/ 44^{( . )}
A61K 31/ 4406^{( . )}
A61P 11/ 00^{( . )}
A61P 15/ 00^{( . )}
A61P 19/ 00^{( . )}
A61P 25/ 28^{( . )}
A61P 27/ 02^{( . )}
A61P 29/ 00^{( . )}
A61P 35/ 04^{( . )}
A61P 43/ 00^{( . )}
C07D 213/ 61^{( . )}

(86)	International application number:
	PCT/CA1997/000270

(87)	International publication number:
	WO 1997/040012 (30.10.1997 Gazette 1997/46)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

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Priority:

23.04.1996 US 19960016076P
30.04.1996 GB 19960008813

(71)	Applicant: MERCK FROSST CANADA INC.
	Kirkland Quebec H9H 3L1 (CA)

(72)	Inventors:
	BLACK, Cameron Kirkland, Quebec H9H 3L1 (CA) HUGHES, Greg Kirkland, Quebec H9H 3L1 (CA) WANG, Zhaoyin Kirkland, Quebec H9H 3L1 (CA)

(74)	Representative: Horgan, James Michael Frederic, et al
	Merck & Co., Inc., Terlings Park, Eastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	PYRIDINYL-2-CYCLOPENTEN-1-ONES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS