(19)
(11) EP 0 904 082 A1

(12)

(43) Date of publication:
31.03.1999 Bulletin 1999/13

(21) Application number: 97918595.0

(22) Date of filing: 14.04.1997
(51) International Patent Classification (IPC): 
A61K 45/ 00( . )
A61K 31/ 365( . )
A61K 31/ 505( . )
A61K 31/ 529( . )
A61P 9/ 10( . )
A61K 31/ 00( . )
A61K 31/ 366( . )
A61K 31/ 519( . )
A61P 9/ 00( . )
(86) International application number:
PCT/US1997/006127
(87) International publication number:
WO 1997/038694 (23.10.1997 Gazette 1997/45)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 17.04.1996 US 19960015689P
10.06.1996 GB 19960012082
24.06.1996 US 19960020977P
09.08.1996 GB 19960016804

(71) Applicant: MERCK & CO., INC.
Rahway, New Jersey 07065 (US)

(72) Inventor:
  • TOBERT, Jonathan, A.
    Rahway, NJ 07065 (US)

(74) Representative: Thompson, John Dr., et al 
Merck & Co., Inc. European Patent Department Terlings Park Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) COMBINATION THERAPY FOR REDUCING THE RISKS ASSOCIATED WITH CARDIOVASCULAR DISEASE