(19)
(11) EP 0 904 538 A1

(12)

(43) Date of publication:
31.03.1999 Bulletin 1999/13

(21) Application number: 96944237.0

(22) Date of filing: 05.12.1996
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
G01N 33/ 92( . )
(86) International application number:
PCT/US1996/019381
(87) International publication number:
WO 1997/021099 (12.06.1997 Gazette 1997/25)
(84) Designated Contracting States:
DE FR GB IT

(30) Priority: 05.12.1995 US 19950008203P
04.12.1996 US 19960759569

(71) Applicant: EntreMed, Inc.
Rockville, Maryland 20850 (US)

(72) Inventors:
  • DIJKSTRA, Jan
    Libertytown, MD 21762 (US)
  • SWARTZ, Glenn, M., Jr.
    Mt. Airy, Maryland 21771 (US)
  • ANIAGOLU, Jacinta
    Laurel, MD 20723 (US)
  • NACY, Carol, A.
    Bethesda, MD 20817 (US)
  • GREEN, Shawn, J.
    Vienna, VA 22182 (US)

(74) Representative: Patentanwälte Sternagel & Fleischer 
Braunsberger Feld 29
51429 Bergisch Gladbach
51429 Bergisch Gladbach (DE)

   


(54) METHOD OF DIAGNOSIS AND TREATMENT OF ATHEROSCLEROSIS USING ANTI-CHOLESTEROL ANTIBODIES