(19)

(11)

EP 0 906 116 A1

(12)

(43) Date of publication: 07.04.1999 Bulletin 1999/14 (21) Application number: 97927663.0 (22) Date of filing: 21.05.1997

(51) International Patent Classification (IPC):  A61K 9/ 00( . ) A61K 48/ 00( . ) (86) International application number: PCT/US1997/008475 (87) International publication number: WO 1997/044057 (27.11.1997 Gazette 1997/51)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 21.05.1996 US 19960651900 (71) Applicant: Cytotherapeutics, Inc. Lincoln, RI 02865 (US)	(72) Inventors: HAMMANG, Joseph, P. Barrington, RI 02806 (US) BAETGE, E., Edward Barrington, RI 02806 (US) AEBISCHER, Patrick CH-1095 Lutry (CH) RUDNICK, Seth, A. Barrington, RI 02806 (US) (74) Representative: Schlich, George William, et al  Mathys & Squire 100 Grays Inn Road London WC1X 8AL London WC1X 8AL (GB)