HETEROCYCLYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES AS POTASSIUM CHANNEL MODULATORS - Patent 0906282

(19)

(11)

EP 0 906 282 A1

(12)

(43)	Date of publication:
	07.04.1999 Bulletin 1999/14

(21)	Application number: 97928856.0

(22)	Date of filing: 10.06.1997

(51)

International Patent Classification (IPC):

C07D 239/ 26^{( . )}
A61K 31/ 34^{( . )}
A61K 31/ 44^{( . )}
A61K 31/ 4406^{( . )}
A61K 31/ 505^{( . )}
A61P 1/ 12^{( . )}
A61P 13/ 10^{( . )}
C07D 213/ 36^{( . )}
C07D 307/ 81^{( . )}

A61K 31/ 00^{( . )}
A61K 31/ 343^{( . )}
A61K 31/ 4402^{( . )}
A61K 31/ 4409^{( . )}
A61P 1/ 00^{( . )}
A61P 13/ 00^{( . )}
A61P 43/ 00^{( . )}
C07D 213/ 38^{( . )}
C07D 307/ 82^{( . )}

(86)	International application number:
	PCT/US1997/009744

(87)	International publication number:
	WO 1997/048682 (24.12.1997 Gazette 1998/03)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	AL LT LV RO SI

(30)

Priority:

17.06.1996 US 19960664583

(71)	Applicant: AMERICAN HOME PRODUCTS CORPORATION
	Madison, New Jersey 07940-0874 (US)

(72)	Inventors:
	HERBST, David, Richard Wayne, PA 19087 (US) BUTERA, John, Anthony Clarksburg, NJ 08510 (US) GRACEFFA, Russell, Francis Plainsboro, NJ 08536 (US)

(74)	Representative: Mannion, Sally Kim, Dr., et al
	c/o Wyeth Laboratories, Huntercombe Lane South, Taplow Maidenhead, Berkshire SL6 0PH Maidenhead, Berkshire SL6 0PH (GB)

(54)	HETEROCYCLYLMETHYLAMINO DERIVATIVES OF CYCLOBUTENE-3,4-DIONES AS POTASSIUM CHANNEL MODULATORS