(19)
(11) EP 0 907 661 A1

(12)

(43) Date of publication:
14.04.1999 Bulletin 1999/15

(21) Application number: 97927814.0

(22) Date of filing: 30.05.1997
(51) International Patent Classification (IPC): 
A61K 45/ 00( . )
A61K 38/ 04( . )
A61K 38/ 48( . )
A61P 19/ 02( . )
A61P 29/ 00( . )
A61P 37/ 08( . )
C07C 279/ 14( . )
C07C 311/ 10( . )
C07K 14/ 435( . )
C07K 14/ 75( . )
C07K 16/ 28( . )
C12N 9/ 64( . )
A61K 38/ 00( . )
A61K 38/ 16( . )
A61K 39/ 395( . )
A61P 27/ 02( . )
A61P 35/ 00( . )
A61P 43/ 00( . )
C07C 311/ 06( . )
C07D 263/ 38( . )
C07K 14/ 705( . )
C07K 14/ 78( . )
C07K 19/ 00( . )
(86) International application number:
PCT/US1997/009099
(87) International publication number:
WO 1997/045447 (04.12.1997 Gazette 1997/52)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV RO SI

(30) Priority: 31.05.1996 US 19960018733P
31.05.1996 US 19960015869P

(71) Applicant: The Scripps Research Institute
La Jolla, CA 92037 (US)

(72) Inventors:
  • BROOKS, Peter
    San Diego, CA 92122 (US)
  • CHERESH, David, A.
    Cardiff, CA 92007 (US)
  • FRIEDLANDER, Martin
    Del Mar, CA 92014 (US)

(74) Representative: Fisher, Adrian John 
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) METHODS AND COMPOSITIONS USEFUL FOR INHIBITION OF alpha v beta 5 MEDIATED ANGIOGENESIS