METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS - Patent 0910384

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EP 0 910 384 A1

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(43)	Date of publication:
	28.04.1999 Bulletin 1999/17

(21)	Application number: 97915044.0

(22)	Date of filing: 12.03.1997

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International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61P 3/ 00^{( . )}
A61P 11/ 00^{( . )}
A61P 29/ 00^{( . )}
A61P 37/ 00^{( . )}
A61P 43/ 00^{( . )}

A61K 31/ 695^{( . )}
A61P 3/ 10^{( . )}
A61P 11/ 06^{( . )}
A61P 35/ 00^{( . )}
A61P 37/ 06^{( . )}

(86)	International application number:
	PCT/US1997/003928

(87)	International publication number:
	WO 1997/040837 (06.11.1997 Gazette 1997/47)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV RO SI

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Priority:

30.04.1996 US 19960641474

(71)	Applicant: HOECHST MARION ROUSSEL, INC.
	Cincinnati OH 45215-6300 (US)

(72)	Inventors:
	WRIGHT, Paul, S. Cincinnati, OH 45242 (US) BUSCH, Steven, J. Stewartsville, N.J. 08886 (US)

(74)	Representative: Macchetta, Francesco, et al
	Gruppo Lepetit S.p.A. Patent Department Viale Gran Sasso, 18 I-20131 Milano I-20131 Milano (IT)

(54)	METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS