(19)
(11) EP 0 910 653 A2

(12)

(43) Date of publication:
28.04.1999 Bulletin 1999/17

(21) Application number: 97921403.0

(22) Date of filing: 25.04.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 31/ 7088( . )
C12N 5/ 10( . )
C12N 15/ 85( . )
A61K 31/ 70( . )
A61K 48/ 00( . )
C12N 15/ 67( . )
C12N 15/ 88( . )
(86) International application number:
PCT/US1997/007030
(87) International publication number:
WO 1997/041243 (06.11.1997 Gazette 1997/47)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 26.04.1996 US 19960016304P

(71) Applicant: UNIVERSITY OF PITTSBURGH
Pittsburgh, Pennsylvania 15260 (US)

(72) Inventors:
  • HUANG, Leaf
    Wexford, PA 15090 (US)
  • ROBBINS, Paul
    Mt. Lebanon, PA 15216 (US)
  • JAFFURS, Daniel
    Pittsburgh, PA 15224 (US)
  • BRISSON, Marni
    Pittsburgh, PA 15232 (US)
  • LI, Song
    Pittsburgh, PA 15213 (US)
  • YANG, Jingping
    Pittsburgh, PA 15232 (US)

(74) Representative: Goldin, Douglas Michael 
J.A. KEMP & CO. 14 South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) A CYTOPLASMIC GENE EXPRESSION SYSTEM WHICH UTILIZES A PROKARYOTIC RNA POLYMERASE AUTOGENE