INHIBITION OF MATRIX METALLOPROTEASES BY ACETYLENE CONTAINING COMPOUNDS - Patent 0912496

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(11)

EP 0 912 496 A1

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(43)	Date of publication:
	06.05.1999 Bulletin 1999/18

(21)	Application number: 97923622.0

(22)	Date of filing: 12.05.1997

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International Patent Classification (IPC):

A61K 31/ 40^{( . )}
A61K 31/ 195^{( . )}
A61K 31/ 403^{( . )}
A61P 1/ 02^{( . )}
A61P 13/ 02^{( . )}
A61P 17/ 00^{( . )}
A61P 27/ 02^{( . )}
A61P 35/ 00^{( . )}
A61P 43/ 00^{( . )}
C07C 59/ 90^{( . )}
C07C 69/ 145^{( . )}
C07C 69/ 96^{( . )}
C07C 229/ 38^{( . )}

A61K 31/ 19^{( . )}
A61K 31/ 215^{( . )}
A61K 31/ 4035^{( . )}
A61P 9/ 00^{( . )}
A61P 15/ 00^{( . )}
A61P 25/ 00^{( . )}
A61P 29/ 00^{( . )}
A61P 35/ 02^{( . )}
C07C 59/ 84^{( . )}
C07C 59/ 92^{( . )}
C07C 69/ 95^{( . )}
C07C 229/ 34^{( . )}
C07D 209/ 48^{( . )}

(86)	International application number:
	PCT/US1997/007921

(87)	International publication number:
	WO 1997/043245 (20.11.1997 Gazette 1997/50)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

15.05.1996 US 19960645028

(71)	Applicant: Bayer Corporation
	Pittsburgh, PA 15205-9741 (US)

(72)	Inventors:
	DIXON, Brian, R. Woodbridge, CT 06525 (US) CHEN, Jinshan Hamden, CT 06518 (US)

(74)	Representative: Burkert, Frank, et al
	Bayer AG, Konzernbereich RP Patente und Lizenzen 51368 Leverkusen 51368 Leverkusen (DE)

(54)	INHIBITION OF MATRIX METALLOPROTEASES BY ACETYLENE CONTAINING COMPOUNDS