(19)

(11)

EP 0 914 154 A1

(12)

(43) Date of publication: 12.05.1999 Bulletin 1999/19 (21) Application number: 97916251.0 (22) Date of filing: 25.03.1997

(51) International Patent Classification (IPC):  A61K 39/ 39( . ) (86) International application number: PCT/US1997/005094 (87) International publication number: WO 1998/042374 (01.10.1998 Gazette 1998/39)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: ZONAGEN, INC. The Woodlands, TX 77380 (US)	(72) Inventors: PODOLSKI, Joseph, S. The Woodlands, TX 77381 (US) MARTINEZ, Mitzi, L. Conroe, TX 77306 (US) (74) Representative: Walton, Seán Malcolm, et al  MEWBURN ELLIS, York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)