INHIBITION OF HIV-1 REPLICATION BY ANTISENSE RNA EXPRESSION - Patent 0914423

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EP 0 914 423 A2

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(43)	Date of publication:
	12.05.1999 Bulletin 1999/19

(21)	Application number: 97928151.0

(22)	Date of filing: 06.06.1997

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 48/ 00^{( . )}
C07K 14/ 16^{( . )}
C12N 15/ 113^{( . )}
C12R 1/ 92^{( . )}

A61K 31/ 7105^{( . )}
A61P 31/ 18^{( . )}
C12N 5/ 10^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/EP1997/002952

(87)	International publication number:
	WO 1997/046673 (11.12.1997 Gazette 1998/01)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

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Priority:

06.06.1996 US 19960019232P

(71)	Applicants:
	Novartis AG 4058 Basel (CH) SYSTEMIX, INC. Palo Alto, California 94304 (US)

(72)	Inventors:
	BOEHNLEIN, Ernst Randolph, NJ 07869 (US) ESCAICH, Sonia F-75013 Paris (FR) ILVES, Heini Palo Alto, CA 94306 (US) VERES, Gabor Palo Alto, CA 94301 (US)

(74)	Representative: Becker, Konrad, et al
	Novartis AG Geistiges Eigentum Konzern Patent- und Markenabteilung CH Postfach 4002 Basel 4002 Basel (CH)

(54)	INHIBITION OF HIV-1 REPLICATION BY ANTISENSE RNA EXPRESSION