(19)
(11) EP 0 915 843 A1

(12)

(43) Date of publication:
19.05.1999 Bulletin 1999/20

(21) Application number: 97920699.0

(22) Date of filing: 15.04.1997
(51) International Patent Classification (IPC): 
A61K 31/ 00( . )
A61K 31/ 397( . )
A61P 3/ 10( . )
A61P 17/ 00( . )
A61P 19/ 00( . )
A61P 25/ 04( . )
A61P 39/ 00( . )
A61P 43/ 00( . )
C07D 405/ 12( . )
A61K 31/ 395( . )
A61P 3/ 00( . )
A61P 9/ 00( . )
A61P 17/ 06( . )
A61P 19/ 02( . )
A61P 29/ 00( . )
A61P 39/ 06( . )
C07D 205/ 09( . )
(86) International application number:
PCT/EP1997/001898
(87) International publication number:
WO 1997/041098 (06.11.1997 Gazette 1997/47)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
SI

(30) Priority: 26.04.1996 GB 19960008646
15.11.1996 GB 19960023756
03.12.1996 GB 19960025121

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • LEACH, Colin, Andrew
    Harlow, Essex CM19 5AW (GB)
  • HICKEY, Deirdre, Mary, Bernadette
    Harlow, Essex CM19 5AW (GB)
  • IFE, Robert, John
    Harlow, Essex CM19 5AW (GB)
  • DHANAK, Dashyant
    Collegeville, PA 19426-0989 (US)
  • THEOBALD, Colin
    Harlow, Essex CM19 5AW (GB)

(74) Representative: Connell, Anthony Christopher, et al 
SmithKline Beecham plc Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSES