(19)
(11) EP 0 917 469 A1

(12)

(43) Date of publication:
26.05.1999 Bulletin 1999/21

(21) Application number: 97922438.0

(22) Date of filing: 18.04.1997
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 38/ 22( . )
A61P 19/ 08( . )
A61P 43/ 00( . )
A61K 35/ 12( . )
A61K 31/ 00( . )
A61P 19/ 00( . )
A61P 19/ 10( . )
C12N 5/ 077( . )
(86) International application number:
PCT/US1997/006892
(87) International publication number:
WO 1997/039767 (30.10.1997 Gazette 1997/46)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 19.04.1996 US 19960015647

(71) Applicants:
  • ZymoGenetics, Inc.
    Seattle, WA 98102 (US)
  • University of Washington
    Seattle, WA 98195 (US)

(72) Inventors:
  • DURNAM, Diane, M.
    Seattle, WA 98199 (US)
  • KUIJPER, Joseph, L.
    Bothell, WA 98011 (US)
  • WEIGLE, David, S.
    Bainbridge Island, WA 98110 (US)
  • LIU, Chung, C.
    Seattle, WA 98115 (US)

(74) Representative: Bizley, Richard Edward, et al 
Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Baker's Lane
Epping Essex CM16 5DQ
Epping Essex CM16 5DQ (GB)

   


(54) METHODS FOR INDUCING BONE FORMATION