(19)

(11)

EP 0 918 531 A2

(12)

(43) Date of publication: 02.06.1999 Bulletin 1999/22 (21) Application number: 97935765.0 (22) Date of filing: 04.08.1997

(51) International Patent Classification (IPC):  A61K 35/ 74( . ) (86) International application number: PCT/IT1997/000201 (87) International publication number: WO 1998/006411 (19.02.1998 Gazette 1998/07)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: LT LV RO SI (30) Priority: 09.08.1996 IT 1996RM00571 (71) Applicant: DICOFARM S.P.A. I-00191 Roma (IT)	(72) Inventor: GUANDALINI, Stefano I-80018 Mugnano Di Napoli (IT) (74) Representative: Sarpi, Maurizio  Studio FERRARIO Via Collina, 36 00187 Roma 00187 Roma (IT)