8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS - Patent 0918757

(19)

(11)

EP 0 918 757 A1

(12)

(43)	Date of publication:
	02.06.1999 Bulletin 1999/22

(21)	Application number: 97925564.0

(22)	Date of filing: 09.05.1997

(51)

International Patent Classification (IPC):

A61K 31/ 00^{( . )}
A61P 35/ 00^{( . )}

A61K 31/ 395^{( . )}
C07D 245/ 06^{( . )}

(86)	International application number:
	PCT/US1997/008141

(87)	International publication number:
	WO 1997/043268 (20.11.1997 Gazette 1997/50)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30)

Priority:

10.05.1996 US 19960017532P

(71)	Applicant: GEORGETOWN UNIVERSITY
	Washington, DC 20057 (US)

(72)	Inventors:
	KOZIKOWSKI, Alan, P. Princeton, NJ 08540 (US) MA, Dawei, Georgetown University Washington, DC 20057 (US) GLAZER, Robert I. Potomac, MD 20854 (US)

(74)	Representative: Dzieglewska, Hanna Eva
	Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)

(54)	8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS