(19)
(11) EP 0 918 788 A1

(12)

(43) Date of publication:
02.06.1999 Bulletin 1999/22

(21) Application number: 97933344.0

(22) Date of filing: 08.07.1997
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 39/ 395( . )
C07H 21/ 04( . )
C07K 14/ 82( . )
C12N 1/ 21( . )
C12P 21/ 02( . )
C12Q 1/ 02( . )
G01N 33/ 566( . )
A61K 38/ 00( . )
 A61K 39/ 00( . )
A61P 35/ 00( . )
C07K 14/ 47( . )
C07K 16/ 32( . )
C12N 15/ 09( . )
C12P 21/ 08( . )
C12Q 1/ 68( . )
G01N 33/ 574( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1997/011946
(87) International publication number:
WO 1998/001460 (15.01.1998 Gazette 1998/02)
(84) Designated Contracting States:
CH DE ES FR GB IT LI NL

(30) Priority: 08.07.1996 US 19960015863P

(71) Applicant: BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM
Austin, Texas 78701 (US)

(72) Inventors:
  • LEE, Wen-Hwa
    San Antonio, TX 78253 (US)
  • CHEN, Yumay
    San Antonio, TX 78245 (US)
  • CHEN, Chi-Fen
    San Antonio, TX 78245 (US)
  • CHEN, Phang-Lang
    San Antonio, TX 78245 (US)
  • FARMER, Andrew, A.
    San Antonio, TX 78245 (US)
  • JONES, Diane, C.
    San Antonio, TX 78250 (US)
  • ALLRED, D., Craig
    San Antonio, TX 78248 (US)
  • OSBORNE, C., Kent
    San Antonio, TX 78209 (US)

(74) Representative: Gowshall, Jonathan Vallance 
FORRESTER & BOEHMERT Franz-Joseph-Strasse 38
80801 München
80801 München (DE)

   


(54) BRCA1 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF BREAST CANCER