(19)

(11)

EP 0 918 847 A2

(12)

(43) Date of publication: 02.06.1999 Bulletin 1999/22 (21) Application number: 97938120.0 (22) Date of filing: 13.08.1997

(51) International Patent Classification (IPC):  C12N 5/ 0783( . ) A61K 38/ 00( . ) C12N 5/ 0784( . ) (86) International application number: PCT/US1997/013759 (87) International publication number: WO 1998/006823 (19.02.1998 Gazette 1998/07)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 14.08.1996 US 19960696747 11.04.1997 US 19970840213 31.07.1997 US 19970904124 (71) Applicant: Nexell Therapeutics Inc. Irvine, CA 92618-1605 (US)	(72) Inventors: VACHULA, Mona Lake Villa, IL 60046 (US) VAN EPPS, Dennis, E. Cary, IL 60013 (US) ALZONA, Mortimer, T. Vernon Hills, IL 60061 (US) AONO, Frederick, M. Arlington Heights, IL 60004 (US) (74) Representative: UEXKÜLL & STOLBERG  Patentanwälte Beselerstrasse 4 22607 Hamburg 22607 Hamburg (DE)