(19)

(11)

EP 0 920 539 A1

(12)

(43) Date of publication: 09.06.1999 Bulletin 1999/23 (21) Application number: 98924998.0 (22) Date of filing: 29.05.1998

(51) International Patent Classification (IPC):  C07H 21/ 04( . ) C12Q 1/ 68( . ) C12P 19/ 34( . ) (86) International application number: PCT/US1998/010965 (87) International publication number: WO 1998/054364 (03.12.1998 Gazette 1998/48)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 30.05.1997 US 19970048170P 03.06.1997 US 19970048381P (60) Divisional application: 05077010.6 / 1634966 (60) Divisional application: 10161334.7 / 2216416 (71) Applicant: LXR BIOTECHNOLOGY INC. Richmond, CA 94804 (US)	(72) Inventors: LICHTENSTEIN, Anatoly V. Moscow, 115446 (RU) MELKONYAN, Hovsep, S. Albany, CA 94706 (US) UMANSKY, Samuil, R. Richmond, CA 94805 (US) (74) Representative: Bassett, Richard Simon  Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)