(19)

(11)

EP 0 922 033 A1

(12)

(43) Date of publication: 16.06.1999 Bulletin 1999/24 (21) Application number: 96930045.0 (22) Date of filing: 16.08.1996

(51) International Patent Classification (IPC):  A61K 31/ 44( . ) C07D 213/ 80( . ) A61P 29/ 00( . ) (86) International application number: PCT/EP1996/003610 (87) International publication number: WO 1998/007701 (26.02.1998 Gazette 1998/08)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: HANDFORTH INVESTMENTS LTD. Douglas, Isle of Man (GB)	(72) Inventors: ALDOMA, Gustavo Enrique 1426 Buenos Aires (AR) PIATTI, Susana Elida 1426 Buenos Aires (AR) (74) Representative: Wibbelmann, Jobst, Dr., Dipl.-Chem., et al  Wuesthoff & Wuesthoff, Patent- und Rechtsanwälte, Schweigerstrasse 2 81541 München 81541 München (DE)