(19)
(11) EP 0 923 552 A1

(12)

(43) Date of publication:
23.06.1999 Bulletin 1999/25

(21) Application number: 97938009.0

(22) Date of filing: 22.07.1997
(51) International Patent Classification (IPC): 
A61K 31/ 403( . )
A61P 19/ 02( . )
A61P 35/ 00( . )
C07D 491/ 04( . )
A61K 31/ 407( . )
A61P 25/ 28( . )
C07D 209/ 88( . )
C07D 491/ 052( . )
(86) International application number:
PCT/US1997/012782
(87) International publication number:
WO 1998/004527 (05.02.1998 Gazette 1998/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV RO SI

(30) Priority: 26.07.1996 US 19960687849

(71) Applicant: AMERICAN HOME PRODUCTS CORPORATION
Madison, New Jersey 07940-0874 (US)

(72) Inventors:
  • KREFT, Anthony, Frank, III
    Langhorne, PA 19047 (US)
  • CAUFIELD, Craig, Eugene
    Princeton Junction, NJ 08550 (US)
  • FAILLI, Amedeo, Arturo
    Princeton Junction, NJ 08550 (US)
  • CAGGIANO, Thomas, Joseph
    Morrisville, PA 19067 (US)
  • GREENFIELD, Alexander, Aleksey
    Princeton Junction, NJ 08550 (US)
  • KUBRAK, Dennis, Michael
    Philadelphia, PA 19134 (US)

(74) Representative: Connelly, Michael John 
c/o Patent Department Wyeth Laboratories Huntercombe Lane South Taplow
Maidenhead Berkshire SL6 0PH
Maidenhead Berkshire SL6 0PH (GB)

   


(54) PYRANOINDOLE AND CARBAZOLE INHIBITORS OF COX-2