(19)

(11)

EP 0 923 580 A1

(12)

(43) Date of publication: 23.06.1999 Bulletin 1999/25 (21) Application number: 97924560.0 (22) Date of filing: 02.05.1997

(51) International Patent Classification (IPC):  C07D 213/ 74( . ) A61K 31/ 454( . ) A61K 31/ 496( . ) A61P 3/ 06( . ) A61P 5/ 50( . ) A61P 9/ 12( . ) A61P 25/ 28( . ) C07D 417/ 12( . ) A61K 31/ 4439( . ) A61K 31/ 4709( . ) A61K 31/ 5377( . ) A61P 3/ 10( . ) A61P 9/ 10( . ) A61P 13/ 12( . ) C07D 401/ 04( . ) C07D 417/ 14( . ) (86) International application number: PCT/US1997/007415 (87) International publication number: WO 1997/041120 (06.11.1997 Gazette 1997/47)

(84) Designated Contracting States: CH DE FR GB LI SE (30) Priority: 26.07.1996 US 19960687840 (71) Applicants: DR. REDDY'S RESEARCH FOUNDATION Hyderabad, 500 016 Andhra Pradesh (IN) Reddy-Cheminor, Inc. Ridgewood, NJ 07450 (US)

(72) Inventors: LOHRAY, Vidya, Bhushan Hyderabad - 500 033, Andhra Pradesh (IN) LOHRAY, Braj, Bhushan Hyderabad - 500 033, Andhra Pradesh (IN) ALLA, Sekar, Reddy Hyderabad - 500 050, Andhra Pradesh (IN) PARASELLI, Rao, Bheema Hyderabad - 500 050, Andhra Pradesh (IN) RAMANUJAM, Rajagopalan, 28, Vishaal Towers Hyderabad - 500 873, Andhra Pradesh (IN) CHAKRABARTI, Ranjan Hyderabad - 500 038, Andhra Pradesh (IN) (74) Representative: Baillie, Iain Cameron  c/o Ladas & Parry Altheimer Eck 2 80331 Munichen 2 80331 Munichen 2 (DE)