(19)

(11)

EP 0 925 072 A2

(12)

(43) Date of publication: 30.06.1999 Bulletin 1999/26 (21) Application number: 97940711.0 (22) Date of filing: 05.09.1997

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61P 3/ 06( . ) A61K 38/ 20( . ) (86) International application number: PCT/US1997/015308 (87) International publication number: WO 1998/009644 (12.03.1998 Gazette 1998/10)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE Designated Extension States: LT LV RO (30) Priority: 06.09.1996 US 19960706545 (71) Applicant: SCHERING CORPORATION Kenilworth, NJ 07030 (US)	(72) Inventor: CUTLER, David Morristown, NJ 07960 (US) (74) Representative: Ritter, Stephen David, et al  Mathys & Squire 100 Grays Inn Road London WC1X 8AL London WC1X 8AL (GB)