(19)
(11) EP 0 929 668 A1

(12)

(43) Date of publication:
21.07.1999 Bulletin 1999/29

(21) Application number: 97935333.0

(22) Date of filing: 06.08.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61P 43/ 00( . )
C07K 14/ 47( . )
C12N 1/ 15( . )
C12N 1/ 21( . )
C12N 15/ 12( . )
C12P 21/ 08( . )
A61K 38/ 00( . )
C07K 14/ 435( . )
C07K 16/ 18( . )
C12N 1/ 19( . )
C12N 5/ 10( . )
C12P 21/ 02( . )
(86) International application number:
PCT/US1997/013944
(87) International publication number:
WO 1998/010066 (12.03.1998 Gazette 1998/10)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 04.09.1996 US 19960025601P

(71) Applicant: ONYX PHARMACEUTICALS, INC.
Richmond, CA 94806 (US)

(72) Inventors:
  • RUBINFELD, Bonnee
    Danville, CA 94526 (US)
  • POLAKIS, Paul
    Mill Valley, CA 94941 (US)
  • LIGENFELTER, Carol
    Oakland, CA 94610 (US)
  • VUONG, Terilyn, T.
    Oakland, CA 94602 (US)

(74) Representative: Cripps, Joanna Elizabeth, et al 
Mewburn Ellis York House 23 Kingsway
GB-London WC2B 6HP
GB-London WC2B 6HP (GB)

   


(54) MODULATORS OF BRCA1 ACTIVITY