(19)
(11) EP 0 930 892 A1

(12)

(43) Date of publication:
28.07.1999 Bulletin 1999/30

(21) Application number: 97910921.0

(22) Date of filing: 15.10.1997
(51) International Patent Classification (IPC): 
A61K 9/ 50( . )
A61K 35/ 12( . )
A61K 39/ 00( . )
A61P 35/ 00( . )
 A61K 9/ 00( . )
A61K 38/ 00( . )
A61K 47/ 30( . )
A61K 48/ 00( . )
(86) International application number:
PCT/US1997/018455
(87) International publication number:
WO 1998/016246 (23.04.1998 Gazette 1998/16)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 16.10.1996 US 19960731597

(71) Applicant: THE JOHNS HOPKINS UNIVERSITY
Baltimore, MD 21205 (US)

(72) Inventors:
  • BREM, Henry
    Lutherville, MD 21093 (US)
  • PARDOLL, Drew, M.
    Brookeville, MD 20833 (US)
  • THOMPSON, Reid, C.
    Daly City, CA 94014 (US)
  • JAFFEE, Elizabeth, M.
    Lutherville, MD 21093 (US)
  • LEONG, Kam, W.
    Ellicott City, MD 21043 (US)
  • EWEND, Matthew, G.
    Chapel Hill, NC 27514 (US)

(74) Representative: Bassett, Richard Simon 
Eric Potter Clarkson, Park View House, 58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) CYTOKINE ENHANCED IMMUNOTHERAPY FOR BRAIN TUMORS