MATRIX METALLOPROTEINASE INHIBITORS AND THEIR THERAPEUTIC USES - Patent 0931045

(19)

(11)

EP 0 931 045 A1

(12)

(43)	Date of publication:
	28.07.1999 Bulletin 1999/30

(21)	Application number: 97939527.0

(22)	Date of filing: 22.08.1997

(51)

International Patent Classification (IPC):

A61K 31/ 343^{( . )}
A61K 31/ 403^{( . )}
A61P 9/ 04^{( . )}
A61P 17/ 02^{( . )}
A61P 27/ 02^{( . )}
A61P 35/ 00^{( . )}
C07C 311/ 19^{( . )}
C07D 307/ 91^{( . )}

A61K 31/ 381^{( . )}
A61P 1/ 02^{( . )}
A61P 9/ 10^{( . )}
A61P 19/ 02^{( . )}
A61P 29/ 00^{( . )}
A61P 43/ 00^{( . )}
C07D 209/ 88^{( . )}
C07D 333/ 76^{( . )}

(86)	International application number:
	PCT/US1997/014859

(87)	International publication number:
	WO 1998/009934 (12.03.1998 Gazette 1998/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	AL LT LV SI

(30)

Priority:

04.09.1996 US 19960025062P
07.08.1997 US 19970055713P

(71)	Applicant: WARNER-LAMBERT COMPANY
	Morris Plains New Jersey 07950 (US)

(72)	Inventors:
	O'BRIEN, Patrick, Michael Stockbridge, MI 49285 (US) PICARD, Joseph, Armand Canton, MI 48187 (US) SLISKOVIC, Drago, Robert Saline, MI 48176 (US) WHITE, Andrew, David Pinckney, MI 48169 (US)

(74)	Representative: Mansmann, Ivo, et al
	Warner-Lambert Company, Legal Division, Patent Department, c/o Gödecke AG, Mooswaldallee 1 79090 Freiburg 79090 Freiburg (DE)

(54)	MATRIX METALLOPROTEINASE INHIBITORS AND THEIR THERAPEUTIC USES