(19)
(11) EP 0 931 138 A1

(12)

(43) Date of publication:
28.07.1999 Bulletin 1999/30

(21) Application number: 97910881.0

(22) Date of filing: 10.10.1997
(51) International Patent Classification (IPC): 
A61K 35/ 28( . )
A61K 39/ 02( . )
A61K 39/ 21( . )
A61K 48/ 00( . )
A61P 25/ 00( . )
A61P 31/ 22( . )
A61P 37/ 06( . )
C12N 5/ 0784( . )
A61K 38/ 00( . )
 A61K 39/ 00( . )
A61K 39/ 12( . )
A61K 39/ 245( . )
A61P 3/ 10( . )
A61P 31/ 18( . )
A61P 35/ 00( . )
C12N 5/ 078( . )
C12N 5/ 10( . )
(86) International application number:
PCT/US1997/018317
(87) International publication number:
WO 1998/015615 (16.04.1998 Gazette 1998/15)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 10.10.1996 US 19960031445P

(71) Applicant: DUKE UNIVERSITY
Durham, North Carolina 27708-0083 (US)

(72) Inventors:
  • HAYNES, Barton, F.
    Durham, NC 27707 (US)
  • PATEL, Dhavalkumar, D.
    Durham, NC 27712 (US)
  • SMITH, Clayton, A.
    Durham, NC 27707 (US)
  • MIRALLES, G., Diego
    Hillsborough, NC 27278 (US)

(74) Representative: Walton, Seán Malcolm, et al 
MEWBURN ELLIS, York House, 23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) METHOD OF PRODUCING A THYMIC MICROENVIRONMENT THAT SUPPORTS THE DEVELOPMENT OF DENDRITIC CELLS