(19)

(11)

EP 0 932 608 A1

(12)

(43) Date of publication: 04.08.1999 Bulletin 1999/31 (21) Application number: 97911745.0 (22) Date of filing: 10.10.1997

(51) International Patent Classification (IPC):  A61K 38/ 00( . ) A61P 9/ 02( . ) C07D 417/ 12( . ) C07K 5/ 06( . ) A61P 7/ 02( . ) A61P 9/ 10( . ) C07F 5/ 02( . ) (86) International application number: PCT/US1997/018647 (87) International publication number: WO 1998/016525 (23.04.1998 Gazette 1998/16)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 11.10.1996 US 19960731361 11.10.1996 US 19960035154P 10.10.1997 US 19970948482 (71) Applicant: COR THERAPEUTICS, INC. South San Francisco, CA 94080 (US)	(72) Inventors: ZHU, Bing-Yan Foster City, CA 94404 (US) SCARBOROUGH, Robert, M. Belmont, CA 94002 (US) (74) Representative: Mouget-Goniot, Claire  Cabinet Orès, 6, Avenue de Messine 75008 Paris 75008 Paris (FR)