(19)

(11)

EP 0 935 608 A1

(12)

(43) Date of publication: 18.08.1999 Bulletin 1999/33 (21) Application number: 97941730.0 (22) Date of filing: 26.09.1997

(51) International Patent Classification (IPC):  C07K 5/ 072( . ) C07K 5/ 097( . ) C07K 14/ 16( . ) A61K 38/ 00( . ) C07K 5/ 087( . ) C07K 7/ 06( . ) G01N 33/ 50( . ) (86) International application number: PCT/AU1997/000640 (87) International publication number: WO 1998/013377 (02.04.1998 Gazette 1998/13)

(84) Designated Contracting States: AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 27.09.1996 AU 1996PO02659 30.09.1996 AU 1996PO02680 (71) Applicant: BIOMOLECULAR RESEARCH INSTITUTE LTD. Parkville, VIC 3052 (AU)

(72) Inventors: AZAD, Ahmed Parkville, VIC 3052 (AU) LOWE, Melinda Parkville, VIC 3052 (AU) CURTAIN, Cyril Parkville, VIC 3052 (AU) BAELL, Jonathan Parkville, VIC 3052 (AU) MATTHEWS, Barry Parkville, VIC 3052 (AU) MACREADIE, Ian Parkville, VIC 3052 (AU) ARUNAGIRI, Chinniah Parkville, VIC 3052 (AU) RIVETT, Don Canterbury, VIC 3126 (AU) NORTON, Raymond Parkville, VIC 3052 (AU) BARNHAM, Kevin Parkville, VIC 3052 (AU) (74) Representative: Schlich, George William, et al  Mathys & Squire 100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)