(19)

(11)

EP 0 935 756 A2

(12)

(43) Date of publication: 18.08.1999 Bulletin 1999/33 (21) Application number: 97910562.0 (22) Date of filing: 03.11.1997

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) G01N 33/ 564( . ) C12Q 1/ 26( . ) G01N 33/ 573( . ) (86) International application number: PCT/GB1997/003014 (87) International publication number: WO 1998/020354 (14.05.1998 Gazette 1998/19)

(84) Designated Contracting States: CH DE ES FR GB IT LI SE (30) Priority: 01.11.1996 GB 19960022772 (71) Applicant: RSR LIMITED Pentwyn, Cardiff CF2 7HE (GB)	(72) Inventors: GRENNAN JONES, Fiona Caerphilly CF83 3HF (GB) FURMANIAK, Jadwiga Cardiff CF4 9HX (GB) REES SMITH, Bernard Cardiff CF3 9BX (GB) (74) Representative: Austin, Hedley William  Urquhart-Dykes & Lord Alexandra House 1 Alexandra Road Swansea Wales SA1 5ED Swansea Wales SA1 5ED (GB)