(19)
(11) EP 0 937 079 A1

(12)

(43) Date of publication:
25.08.1999 Bulletin 1999/34

(21) Application number: 97913772.0

(22) Date of filing: 24.10.1997
(51) International Patent Classification (IPC): 
C07D 477/ 00( . )
A61K 31/ 454( . )
A61P 31/ 04( . )
C07D 477/ 20( . )
A61K 31/ 407( . )
A61K 31/ 496( . )
C07D 477/ 02( . )
(86) International application number:
PCT/US1997/019336
(87) International publication number:
WO 1998/018800 (07.05.1998 Gazette 1998/18)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

(30) Priority: 28.10.1996 US 19960029520P
18.12.1996 GB 19960026211

(71) Applicant: Merck & Co., Inc. (a New Jersey corp.)
Rahway, N.J. 07065 (US)

(72) Inventors:
  • ALMARSSON, Orn
    Rahway, NJ 07065 (US)
  • KAUFMAN, Michael, J.
    Rahway, NJ 07065 (US)
  • STONG, John, D.
    Rahway, NJ 07065 (US)
  • WILLIAMS, John, M.
    Rahway, NJ 07065 (US)

(74) Representative: Hiscock, Ian James, et al 
European Patent Department, Merck & Co., Inc., Terlings Park, Eastwick Road
Harlow, Essex CM20 2QR
Harlow, Essex CM20 2QR (GB)

   


(54) STABILIZED CARBAPENEM ANTIBIOTIC COMPOSITIONS AND METHOD OF MAKING