(19)
(11) EP 0 937 143 A2

(12)

(43) Date of publication:
25.08.1999 Bulletin 1999/34

(21) Application number: 97936173.0

(22) Date of filing: 23.07.1997
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 39/ 00( . )
A61P 1/ 04( . )
A61P 19/ 00( . )
A61P 31/ 00( . )
A61P 37/ 02( . )
C07K 14/ 47( . )
C12N 1/ 19( . )
C12N 5/ 10( . )
C12P 21/ 02( . )
 A61K 38/ 00( . )
A61K 48/ 00( . )
A61P 17/ 02( . )
A61P 25/ 00( . )
A61P 35/ 00( . )
A61P 43/ 00( . )
C12N 1/ 15( . )
C12N 1/ 21( . )
C12N 15/ 12( . )
C12Q 1/ 68( . )
(86) International application number:
PCT/US1997/012884
(87) International publication number:
WO 1998/004694 (05.02.1998 Gazette 1998/05)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 26.07.1996 US 19960686878
23.08.1996 US 19960702081

(71) Applicant: GENETICS INSTITUTE, INC.
Cambridge, Massachusetts 02140 (US)

(72) Inventors:
  • JACOBS, Kenneth
    Newton, MA 02160 (US)
  • MCCOY, John, M.
    Reading, MA 01867 (US)
  • LAVALLIE, Edward, R.
    Harvard, Massachusetts 01451 (US)
  • RACIE, Lisa, A.
    Acton, MA 01720 (US)
  • MERBERG, David
    Acton, MA 01720 (US)
  • TREACY, Maurice
    Chestnut Hill, MA 02167 (US)
  • SPAULDING, Vikki
    Billerica, MA 01821 (US)

(74) Representative: Frohwitter, Bernhard, Dipl.-Ing. 
Patent- und Rechtsanwälte, Possartstrasse 20
81679 München
81679 München (DE)

   


(54) SECRETED PROTEINS AND POLYNUCLEOTIDES ENCODING THEM