(19)
(11) EP 0 938 480 A1

(12)

(43) Date of publication:
01.09.1999 Bulletin 1999/35

(21) Application number: 97946555.0

(22) Date of filing: 10.11.1997
(51) International Patent Classification (IPC): 
A61K 31/ 53( . )
A61P 9/ 10( . )
A61P 3/ 00( . )
C07D 251/ 08( . )
(86) International application number:
PCT/US1997/020233
(87) International publication number:
WO 1998/021190 (22.05.1998 Gazette 1998/20)
(84) Designated Contracting States:
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
Designated Extension States:
AL LT LV RO SI

(30) Priority: 14.11.1996 US 19960748876

(71) Applicant: AMERICAN HOME PRODUCTS CORPORATION
Madison, New Jersey 07940-0874 (US)

(72) Inventors:
  • MEMOLI, Kevin, Anthony
    Cranbury, NJ 08512 (US)
  • STRIKE, Donald, Peter
    St. Davids, PA 19087 (US)
  • FAILLI, Amedeo, Arturo
    Princeton Junction, NJ 08550 (US)
  • STEFFAN, Robert, John
    Langhorne, PA 19047 (US)

(74) Representative: Talbott, Dawn Jacqueline, et al 
Wyeth Laboratories, Patent Department, Huntercombe Lane South, Taplow
Maidenhead, Berkshire SL6 0PH
Maidenhead, Berkshire SL6 0PH (GB)

   


(54) SUBSTITUTED TETRAHYDRO-1,3,5-TRIAZIN-2 1H]-THIONES AS ANTI-ATHEROSCLEROTIC AGENTS